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. 1978 May 1;171(2):337–347. doi: 10.1042/bj1710337

Sequence of the full-length immunoglobulin kappa-chain of mouse myeloma MPC 11.

G P Smith
PMCID: PMC1183962  PMID: 418775

Abstract

MPC 11 mouse myeloma cells synthesize two immunoglobulin kappa light chains, coded by two separate genes. One of these Kappa-chains has no variable region and is degraded intracellularly. The other is a full-length kappa-chain contaning both variable and constant regions: this chain is secreted, both by itself and combined with heavy chains in molecules of immunoglobulin G. This paper reports the amino acid sequence of the myeloma MPC 11 full-length kappa-chain. The chain is unusual in having 12 extra residues at its N-terminus when its sequence is aligned with those of other mouse kappa-chains; no other anomalies were found in its sequence.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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