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. 1965 Feb;8(2):206–212.

Distribution of allotypic specificities on the peptide chains of human gamma-globulin

Sylvia D Lawler, S Cohen
PMCID: PMC1423435  PMID: 14295644

Abstract

The peptide chains (A and B) isolated from the 7S γ-globulin of a single donor known to be Gm(a+ b+) and Inv(a+), were tested for the presence of allotypic specificities. Gm factors were present only on the A chain and the Inv factor was found only on the B chain. Ten pathological B chains, of which five were antigenic type I and five type II, were studied; all were negative for Inv(a), but Inv(b) specificity appeared to be associated with B chains of both antigenic types.

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Selected References

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