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. 1983 Aug;80(15):4694–4698. doi: 10.1073/pnas.80.15.4694

A precise termination site in the mouse beta major-globin transcription unit.

M Salditt-Georgieff, J E Darnell Jr
PMCID: PMC384110  PMID: 6192441

Abstract

Nascent labeled RNA from induced, globin-producing mouse erythroleukemia cells was hybridized to cloned regions of the beta major-globin gene. Transcription ceases about 1,000 bases downstream from the poly(A) site as indicated by protection from nuclease digestion of a discrete-sized RNA fragment that it shorter than the protecting cloned DNA fragment. This defines an apparently unique termination site for a protein-coding gene that is transcribed by RNA polymerase II.

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Selected References

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