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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1977 Jul;74(7):2985–2988. doi: 10.1073/pnas.74.7.2985

Production of antibodies against influenza virus by somatic cell hybrids between mouse myeloma and primed spleen cells.

H Koprowski, W Gerhard, C M Croce
PMCID: PMC431374  PMID: 268647

Abstract

We have produced somatic cell hybrids between mouse myeloma cells and spleen cells derived from a BALB/c mouse immunized with purified influenza virus. The hybrid cells were found to produce large amounts of antibodies specific for the hemagglutinin of the virus and were able to induce tumor formation when injected into BALB/c mice.

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Selected References

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